MODULAR COMBINATORIAL DNA ASSEMBLY OF GROUP B STREPTOCOCCUS CAPSULAR POLYSACCHARIDE BIOSYNTHESIS PATHWAYS TO EXPEDIATE THE PRODUCTION OF NOVEL GLYCOCONJUGATE VACCINES

Modular Combinatorial DNA Assembly of Group B Streptococcus Capsular Polysaccharide Biosynthesis Pathways to Expediate the Production of Novel Glycoconjugate Vaccines

Background/objectives: Streptococcus agalactiae (or Group B Streptococcus, GBS) is a major cause of neonatal meningitis globally.There are 10 Bedding serotypes of GBS, which are distinguished by their capsular polysaccharide (CPS) structure, with serotypes Ia, Ib, II, III, IV and V responsible for up to 99% of infections.Currently, there are no lic

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